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SFI Europe and AbbVie announce €10m investment

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SFI Europe and AbbVie announce €10m investment

November 23
09:56 2015

abbvie 2Minister for Jobs Mr Richard Bruton has announced a joint investment of €10 million by the Department of Jobs, Enterprise and Innovation through Science Foundation Ireland (SFI) in a partnership with leading international biopharmaceutical company AbbVie to undertake two new therapeutic research collaborations in Ireland.

The collaborations, which will each investigate disease markers and potential targets against which new drugs could be developed for serious illnesses such as Crohn’s disease, rheumatoid arthritis, psoriasis and multiple sclerosis, are between AbbVie and researchers at the SFI APC Microbiome Institute in University College Cork (UCC) and at the Trinity Biomedical Sciences Institute in Trinity College Dublin.

Announcing the investment, at the Global Irish Economic Forum in Dublin Castle Richard Bruton explained the significance of the joint investment by industry and government, “This clearly demonstrates the importance and value of Government supporting high quality researchers in our academic institutes which enables them to partner with multinational companies to undertake research in Ireland. I wish Jim and his team every success and look forward to working with them in the future.”

“I welcome the establishment of these two new research collaborations by AbbVie.  AbbVie is a world-leading biopharmaceutical company and this builds on considerable investments made by AbbVie in Ireland earlier this year.”

abbvie dublin castleJim Sullivan, Vice President, Pharmaceutical Discovery, AbbVie, said“AbbVie has a long history in Ireland and the country has contributed greatly to our global success. We are impressed with the high quality immunology research ongoing across academia in Ireland. Partnering with the leading researchers in autoimmune disease will foster continued innovation in one of our most important therapeutic areas. We hope to unlock the potential for significant advancements for patients with serious autoimmune disease.”

In Cork, AbbVie will collaborate with researchers at the Science Foundation Ireland Research Centre, the APC Microbiome Institute in UCC led by Prof Fergus Shanahan on identifying possible new treatments for patients with Crohn’s disease. The research will be supported by an investment of €7.5 million from SFI together with AbbVie over five years and will support 11 new research positions at the APC.

Prof Fergus Shanahan, Director of the APC Microbiome Institute, said, “This AbbVie and APC venture is a wonderful match, blending industry and academe with complementary technology and expertise.”

The second project will involve collaboration with researchers led by Prof Kingston Mills, at the Trinity Biomedical Sciences Institute in Trinity, working on biomarkers and drug targets for autoimmune and other immune-mediated diseases. This research will be funded by €2.5million from SFI and AbbVie over the next three years and will support four new research positions.

Prof Kingston Mills, Professor of Experimental Immunology, School of Biochemistry and Immunology, Trinity College Dublin, said, “Inflammation is a vital process in fighting infection, however, if uncontrolled, it can contribute to the development of autoimmune diseases, such as rheumatoid arthritis, psoriasis, Crohn’s disease and multiple sclerosis.  This collaborative research project with AbbVie, a major biopharmaceutical company, will focus on identifying and building our understanding of the cellular and molecular mechanisms that cause inflammation to assist in developing new disease markers and drug targets for the treatment of a range of inflammatory diseases.”

Commenting on the announcement, Prof Mark Ferguson, Director General of Science Foundation Ireland and Chief Scientific Adviser to the Government of Ireland said, “Autoimmune diseases like Crohn’s are common and debilitating. To develop new treatments we need to better understand the underlying mechanisms which is the focus of these research collaborations. By partnering our leading researchers with those in a major pharmaceutical company like AbbVie we can hopefully accelerate the discovery of new knowledge which will lead to improved treatments and outcomes for patients.”

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